Energetics of ion competition in the DEKA selectivity filter of neuronal sodium channels

The energetics of ionic selectivity in the neuronal sodium channels is studied. A simple model constructed for the selectivity filter of the channel is used. The selectivity filter of this channel type contains aspartate (D), glutamate (E), lysine (K), and alanine (A) residues (the DEKA locus). We u...

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Bibliographic Details
Main Authors: D. Boda, G. Leaf, J. Fonseca, B. Eisenberg
Format: Article
Language:English
Published: Institute for Condensed Matter Physics 2015-03-01
Series:Condensed Matter Physics
Subjects:
Online Access:http://dx.doi.org/10.5488/CMP.18.13601