Interplay of Histone Marks with Serine ADP-Ribosylation

Summary: Serine ADP-ribosylation (Ser-ADPr) is a recently discovered protein modification that is catalyzed by PARP1 and PARP2 when in complex with the eponymous histone PARylation factor 1 (HPF1). In addition to numerous other targets, core histone tails are primary acceptors of Ser-ADPr in the DNA...

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Bibliographic Details
Main Authors: Edward Bartlett, Juan José Bonfiglio, Evgeniia Prokhorova, Thomas Colby, Florian Zobel, Ivan Ahel, Ivan Matic
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718314116