Protective Effects of Swertiamarin against Methylglyoxal-Induced Epithelial-Mesenchymal Transition by Improving Oxidative Stress in Rat Kidney Epithelial (NRK-52E) Cells

Protective Effects of Swertiamarin against Methylglyoxal-Induced Epithelial-Mesenchymal Transition by Improving Oxidative Stress in Rat Kidney Epithelial (NRK-52E) Cells

Increased blood glucose in diabetic individuals results in the formation of advanced glycation end products (AGEs), causing various adverse effects on kidney cells, thereby leading to diabetic nephropathy (DN). In this study, the antiglycative potential of Swertiamarin (SM) isolated from the methano...

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Bibliographic Details
Main Authors: Kirti Parwani, Farhin Patel, Dhara Patel, Palash Mandal
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
advanced glycation end product (AGE)
oxidative stress
epithelial to mesenchymal transition
AGE-inhibitor
swertiamarin
diabetic nephropathy
Online Access:https://www.mdpi.com/1420-3049/26/9/2748

Internet

https://www.mdpi.com/1420-3049/26/9/2748

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