The absence of SOX2 in the anterior foregut alters the esophagus into trachea and bronchi in both epithelial and mesenchymal components

The absence of SOX2 in the anterior foregut alters the esophagus into trachea and bronchi in both epithelial and mesenchymal components

In the anterior foregut (AFG) of mouse embryos, the transcription factor SOX2 is expressed in the epithelia of the esophagus and proximal branches of respiratory organs comprising the trachea and bronchi, whereas NKX2.1 is expressed only in the epithelia of respiratory organs. Previous studies using...

Full description

Bibliographic Details
Main Authors: Machiko Teramoto, Ryo Sugawara, Katsura Minegishi, Masanori Uchikawa, Tatsuya Takemoto, Atsushi Kuroiwa, Yasuo Ishii, Hisato Kondoh
Format: Article
Language:English
Published: The Company of Biologists 2020-02-01
Series:Biology Open
Subjects:
anterior foregut
conditional knockout
epithelial-mesenchymal interaction
esophagus
respiratory organ
sox2
Online Access:http://bio.biologists.org/content/9/2/bio048728

Internet

http://bio.biologists.org/content/9/2/bio048728

Similar Items