DASATINIB IN CHRONIC MYELOID LEUKEMIA

BACKGROUND The BCR-ABL tyrosine kinase inhibitor imatinib is effective in Philadelphia chromosomepositive CML (chronic myeloid leukemia), but relaps occurs, mainly as a reults of the outgrowth of leukemic subclones with imatinib resistant BCR-ABL mutation.Some patientswith various phases of CML note...

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Bibliographic Details
Main Author: Mojca Modic
Format: Article
Language:English
Published: Slovenian Medical Association 2008-04-01
Series:Zdravniški Vestnik
Online Access:http://vestnik.szd.si/index.php/ZdravVest/article/view/908