Simultaneous Determination of Three Furanocoumarins by UPLC/MS/MS: Application to Pharmacokinetic Study of Angelica dahurica Radix after Oral Administration to Normal and Experimental Colitis-Induced Rats

Simultaneous Determination of Three Furanocoumarins by UPLC/MS/MS: Application to Pharmacokinetic Study of Angelica dahurica Radix after Oral Administration to Normal and Experimental Colitis-Induced Rats

In traditional oriental medicine, Angelica dahurica Radix (ADR) is used in the treatment of gastrointestinal, respiratory, neuromuscular, and dermal disorders. We evaluated the pharmacokinetic profiles of oxypeucedanin, imperatorin, and isoimperatorin, major active ingredients of ADR, in normal and...

Full description

Bibliographic Details
Main Authors: Youn-Hwan Hwang, Hye Jin Yang, Jin Yeul Ma
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Molecules
Subjects:
Angelica dahurica Radix
imperatorin
isoimperatorin
oxypeucedanin
pharmacokinetics
colitis
Online Access:http://www.mdpi.com/1420-3049/22/3/416

Internet

http://www.mdpi.com/1420-3049/22/3/416

Similar Items