T-Cell Lymphoma Clonality by Copy Number Variation Analysis of T-Cell Receptor Genes

T-Cell Lymphoma Clonality by Copy Number Variation Analysis of T-Cell Receptor Genes

T-cell lymphomas arise from a single neoplastic clone and exhibit identical patterns of deletions in T-cell receptor (TCR) genes. Whole genome sequencing (WGS) data represent a treasure trove of information for the development of novel clinical applications. However, the use of WGS to identify clona...

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Bibliographic Details
Main Authors: Ming Liang Oon, Jing Quan Lim, Bernett Lee, Sai Mun Leong, Gwyneth Shook-Ting Soon, Zi Wei Wong, Evelyn Huizi Lim, Zhenhua Li, Allen Eng Juh Yeoh, Shangying Chen, Kenneth Hon Kim Ban, Tae-Hoon Chung, Soo-Yong Tan, Shih-Sung Chuang, Seiichi Kato, Shigeo Nakamura, Emiko Takahashi, Yong-Howe Ho, Joseph D Khoury, Rex K. H. Au-Yeung, Chee-Leong Cheng, Soon-Thye Lim, Wee-Joo Chng, Claudio Tripodo, Olaf Rotzschke, Choon Kiat Ong, Siok-Bian Ng
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
whole genome sequencing
T-cell receptor
clonality
copy number variation analysis
T-cell lymphoma
Online Access:https://www.mdpi.com/2072-6694/13/2/340

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https://www.mdpi.com/2072-6694/13/2/340

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