SIRT3, a mitochondrial NAD⁺-dependent deacetylase, is involved in the regulation of myoblast differentiation.

Sirtuin 3 (SIRT3), one of the seven mammalian sirtuins, is a mitochondrial NAD+-dependent deacetylase known to control key metabolic pathways. SIRT3 deacetylases and activates a large number of mitochondrial enzymes involved in the respiratory chain, in ATP production, and in both the citric acid an...

Full description

Bibliographic Details
Main Authors: Waed Abdel Khalek, Fabienne Cortade, Vincent Ollendorff, Laure Lapasset, Lionel Tintignac, Béatrice Chabi, Chantal Wrutniak-Cabello
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4260865?pdf=render