Effects of zoledronic acid on osteoblasts in three-dimensional culture

Background/purpose: Bisphosphonates (BPs) are synthetic drugs with antitumor and bone antiresorptive activities. The use of BPs is suspected to favor the emergence of osteonecrosis of the jaw (ONJ), a putative side effect whose pathogenesis remains unclear. Thus, we aimed to get insights about the i...

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Bibliographic Details
Main Authors: Flora Thibaut, Tanguy Watrin, Fleur Meary, Sylvie Tricot, Virginie Legros, Pascal Pellen-Mussi, Dominique Chauvel-Lebret
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Journal of Dental Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1991790214001093