Biomarker discovery by integrated joint non-negative matrix factorization and pathway signature analyses
Abstract Predictive biomarkers are important for selecting appropriate patients for particular treatments. Comprehensive genomic, transcriptomic, and pharmacological data provide clues for understanding relationships between biomarkers and drugs. However, it is still difficult to mine biologically m...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-28066-w |