Cancer Cell B7-H3 Expression Is More Prevalent in the Pancreato-Biliary Subtype of Ampullary Cancer Than in Pancreatic Cancer

Cancer Cell B7-H3 Expression Is More Prevalent in the Pancreato-Biliary Subtype of Ampullary Cancer Than in Pancreatic Cancer

B7-H3 is an immunomodulatory member of the B7-superfamily with limited expression in normal tissues, but overexpression in several types of cancer. Therefore it is currently being explored as a potential target for cancer immunotherapy. The biological relevance of B7-H3 expression in pancreatic canc...

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Bibliographic Details
Main Authors: Emma E. Geerdes, Kostandinos Sideras, M. Hosein Aziz, Casper H. van Eijck, Marco J. Bruno, Dave Sprengers, Patrick P. C. Boor, Jaap Kwekkeboom
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
cancer immunotherapy
CD276
B7H3
immune checkpoint
pancreas
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.615691/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.615691/full

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