Germline Mutations Including the Rare Pathogenic Variant c.3206delC in the <i>ATM</i> Gene Cause Ataxia Teleangiectasia-Associated Primary Central Nervous System Lymphoma

Germline Mutations Including the Rare Pathogenic Variant c.3206delC in the <i>ATM</i> Gene Cause Ataxia Teleangiectasia-Associated Primary Central Nervous System Lymphoma

We here report the case of a 2-year-old patient with a primary central nervous system lymphoma of B-cell origin. Due to their past medical history of repeated respiratory tract infections and the marked chemotherapy-associated toxicity and infectious comorbidity, we suspected that the patient also s...

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Bibliographic Details
Main Authors: Jan R. Dörr, Anne Thorwarth, Agnieszka Mizia-Malarz, Josefine Radke, Anna Tietze, Pablo Hernáiz-Driever, Denise Horn, Alexander Gratopp, Angelika Eggert, Hedwig E. Deubzer
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Children
Subjects:
cancer
cancer predisposition
immune deficiency disorder
multiresistant bacteria
chemotherapy tolerance
Online Access:https://www.mdpi.com/2227-9067/8/6/469

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https://www.mdpi.com/2227-9067/8/6/469

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