Progressive levels of physical dependence to tobacco coincide with changes in the anterior cingulum bundle microstructure.

The tobacco withdrawal syndrome indicates the development of neurophysiologic dependence. Clinical evidence indicates that neurophysiologic dependence develops through a set sequence of symptom presentation that can be assessed with a new 3-item survey measure of wanting, craving, and needing tobacc...

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Bibliographic Details
Main Authors: Wei Huang, Joseph R DiFranza, David N Kennedy, Nanyin Zhang, Douglas Ziedonis, Sanouri Ursprung, Jean A King
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3701580?pdf=render