Histidine-rich glycoprotein as a prognostic biomarker for sepsis

Abstract Various biomarkers have been proposed for sepsis; however, only a few become the standard. We previously reported that plasma histidine-rich glycoprotein (HRG) levels decreased in septic mice, and supplemental infusion of HRG improved survival in mice model of sepsis. Moreover, our previous...

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Bibliographic Details
Main Authors: Kosuke Kuroda, Kenzo Ishii, Yuko Mihara, Naoya Kawanoue, Hidenori Wake, Shuji Mori, Michihiro Yoshida, Masahiro Nishibori, Hiroshi Morimatsu
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89555-z