Multi-species transcriptome meta-analysis of the response to retinoic acid in vertebrates and comparative analysis of the effects of retinol and retinoic acid on gene expression in LMH cells

Abstract Background Retinol (RO) and its active metabolite retinoic acid (RA) are major regulators of gene expression in vertebrates and influence various processes like organ development, cell differentiation, and immune response. To characterize a general transcriptomic response to RA-exposure in...

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Bibliographic Details
Main Authors: Clemens Falker-Gieske, Andrea Mott, Sören Franzenburg, Jens Tetens
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-021-07451-2