Arsenic trioxide induce apoptosis independent of TNFR-I and CD30 pathways in Acute promyelocytic leukemia patient with t(15;17) translocation.

Arsenic trioxide (ATO) has been reported to induce apoptosis in Leukemic cells of Acute Promyelo-cytic Leukemia (APL) patients through different pathways. However, the exact mechanism of ATO-induced apoptosis is not yet clear. Co stimulation of death receptors CD30 and tumor necrosis factor receptor...

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Bibliographic Details
Main Authors: Ardjmand.AR, Alimoghadam. K, Kaviani S, Ghavamzadeh A, Djahani.M, 1 Moezzi L
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2005-06-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4519.pdf&manuscript_id=4519