Isolation and characterizations of a novel recombinant scFv antibody against exotoxin A of Pseudomonas aeruginosa

Isolation and characterizations of a novel recombinant scFv antibody against exotoxin A of Pseudomonas aeruginosa

Abstract Background Pseudomonas aeruginosa is the leading cause of nosocomial infections, especially in people with a compromised immune system. Targeting virulence factors by neutralizing antibodies is a novel paradigm for the treatment of antibiotic-resistant pseudomonas infections. In this respec...

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Bibliographic Details
Main Authors: Zahra Shadman, Safar Farajnia, Mohammad Pazhang, Mohammadreza Tohidkia, Leila Rahbarnia, Saeed Najavand, Sayna Toraby
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Infectious Diseases
Subjects:
Phage display
Pseudomonas aeruginosa
Exotoxin A
Human single chain antibody
Online Access:https://doi.org/10.1186/s12879-021-05969-0

Internet

https://doi.org/10.1186/s12879-021-05969-0

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