Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis

Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis

Abstract Background Expression of matrix metalloproteases 2, 9 and 14 (MMP-2, MMP-9, MMP-14), tissue inhibitors of metalloprotease 1 and 2 (TIMP-1, TIMP-2) and vascular endothelial growth factor A (VEGF-A) is involved in tumor invasion and metastasis via extracellular matrix degradation and angiogen...

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Bibliographic Details
Main Authors: Jordana Maria Azevedo Martins, Silvia Helena Rabelo-Santos, Maria Cristina do Amaral Westin, Luiz Carlos Zeferino
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Cancer
Subjects:
Uterine cervical neoplasms
Matrix metalloproteinase 2
Matrix metalloproteinase 9
Tissue inhibitor of Metalloproteinase-2
Tumor microenvironment
Stroma
Online Access:http://link.springer.com/article/10.1186/s12885-020-07150-3

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http://link.springer.com/article/10.1186/s12885-020-07150-3

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