Impact of Targeted Deletion of the Circadian Clock Gene Bmal1 in Excitatory Forebrain Neurons on Adult Neurogenesis and Olfactory Function

Impact of Targeted Deletion of the Circadian Clock Gene Bmal1 in Excitatory Forebrain Neurons on Adult Neurogenesis and Olfactory Function

The circadian system is an endogenous timekeeping system that synchronizes physiology and behavior with the 24 h solar day. Mice with total deletion of the core circadian clock gene Bmal1 show circadian arrhythmicity, cognitive deficits, and accelerated age-dependent decline in adult neurogenesis as...

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Bibliographic Details
Main Authors: Amira A. H. Ali, Federica Tundo-Lavalle, Soha A. Hassan, Martina Pfeffer, Anna Stahr, Charlotte von Gall
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
circadian clock
neurogenesis
oxidative stress
hippocampus
Online Access:https://www.mdpi.com/1422-0067/21/4/1394

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https://www.mdpi.com/1422-0067/21/4/1394

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