Macrophage-Driven Biomaterial Degradation Depends on Scaffold Microarchitecture

Macrophage-Driven Biomaterial Degradation Depends on Scaffold Microarchitecture

In situ tissue engineering is a technology in which non-cellular biomaterial scaffolds are implanted in order to induce local regeneration of replaced or damaged tissues. Degradable synthetic electrospun scaffolds are a versatile and promising class of biomaterials for various in situ tissue enginee...

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Bibliographic Details
Main Authors: Tamar B. Wissing, Valentina Bonito, Eline E. van Haaften, Marina van Doeselaar, Marieke M. C. P. Brugmans, Henk M. Janssen, Carlijn V. C. Bouten, Anthal I. P. M. Smits
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
in situ tissue engineering
enzymatic degradation
oxidative degradation
reactive oxygen species
electrospinning
macrophage polarization
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00087/full

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https://www.frontiersin.org/article/10.3389/fbioe.2019.00087/full

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