Cancer‐associated V‐ATPase induces delayed apoptosis of protumorigenic neutrophils

Cancer‐associated V‐ATPase induces delayed apoptosis of protumorigenic neutrophils

Tumors and neutrophils undergo an unexpected interaction, in which products released by tumor cells interact to support neutrophils that in turn support cancer growth, angiogenesis, and metastasis. A key protein that is highly expressed by cancer cells in tumors is the a2 isoform V‐ATPase (a2V). A p...

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Bibliographic Details
Main Authors: Safaa A. Ibrahim, Arpita Kulshrestha, Gajendra K. Katara, Valerie Riehl, Manoranjan Sahoo, Kenneth D. Beaman
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Molecular Oncology
Subjects:
cytokines
NF‐κB
TLR2
tumor microenvironment
tumor‐associated neutrophils
vacuolar ATPase
Online Access:https://doi.org/10.1002/1878-0261.12630

Internet

https://doi.org/10.1002/1878-0261.12630

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