Single-strand DNA processing: phylogenomics and sequence diversity of a superfamily of potential prokaryotic HuH endonucleases

Single-strand DNA processing: phylogenomics and sequence diversity of a superfamily of potential prokaryotic HuH endonucleases

Abstract Background Some mobile genetic elements target the lagging strand template during DNA replication. Bacterial examples are insertion sequences IS608 and ISDra2 (IS200/IS605 family members). They use obligatory single-stranded circular DNA intermediates for excision and insertion and encode a...

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Bibliographic Details
Main Authors: Yves Quentin, Patricia Siguier, Mick Chandler, Gwennaele Fichant
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Genomics
Subjects:
HuH superfamily
Transposition
REP sequences
Replication fork
Insertion sequence
RAYT/TnpAREP
Online Access:http://link.springer.com/article/10.1186/s12864-018-4836-1

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http://link.springer.com/article/10.1186/s12864-018-4836-1

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