TRPM7 is involved in acid‐induced necrotic cell death in a manner sensitive to progesterone in human cervical cancer cells

Abstract Because intravaginal pH is strongly acidic, it is important to investigate the effects of acidosis on cervical cancer cells. Recently, in response to strong acidosis, human cervical cancer HeLa cells were shown to exhibit necrosis after showing persistent cell swelling induced by Cl− influx...

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Bibliographic Details
Main Authors: Tomohiro Numata, Kaori Sato‐Numata, Yasunobu Okada
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14157