Mechanisms of DNA damage response to targeted irradiation in organotypic 3D skin cultures.

DNA damage (caused by direct cellular exposure and bystander signaling) and the complex pathways involved in its repair are critical events underpinning cellular and tissue response following radiation exposures. There are limited data addressing the dynamics of DNA damage induction and repair in th...

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Bibliographic Details
Main Authors: Anna Acheva, Mihaela Ghita, Gaurang Patel, Kevin M Prise, Giuseppe Schettino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3914781?pdf=render