Anti-CD22/CD20 Bispecific antibody with enhanced trogocytosis for treatment of Lupus.

The humanized anti-CD22 antibody, epratuzumab, has demonstrated therapeutic activity in clinical trials of lymphoma, leukemia and autoimmune diseases, treating currently over 1500 cases of non-Hodgkin lymphoma, acute lymphoblastic leukemias, Waldenström's macroglobulinemia, Sjögren's syndr...

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Bibliographic Details
Main Authors: Edmund A Rossi, Chien-Hsing Chang, David M Goldenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4026529?pdf=render