A human MIXL1 green fluorescent protein reporter embryonic stem cell line engineered using TALEN-based genome editing

We have generated a MIXL1-eGFP reporter human embryonic stem cell (hESC) line using TALEN-based genome engineering. This line accurately traces endogenous MIXL1 expression via an eGFP reporter to mesendodermal precursor cells. The utility of the MIXL1-eGFP reporter hESC line lies in the prospective...

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Bibliographic Details
Main Authors: Vera Alexeeva, Sunita L. D'Souza, Christoph Schaniel
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116300484