In vivo angiogenesis screening and mechanism of action of novel tanshinone derivatives produced by one-pot combinatorial modification of natural tanshinone mixture from Salvia miltiorrhiza.

Natural products present in low quantity in herb medicines constitute an important source of chemical diversity. However, the isolation of sufficient amounts of these low abundant constituents for structural modification has been a challenge for several decades and subsequently halts research on the...

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Bibliographic Details
Main Authors: Zhe-Rui Zhang, Jin-Hang Li, Shang Li, Ai-Lin Liu, Pui-Man Hoi, Hai-Yan Tian, Wen-Cai Ye, Simon Ming-Yuen Lee, Ren-Wang Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4081027?pdf=render