New Modified Deoxythymine with Dibranched Tetraethylene Glycol Stabilizes G-Quadruplex Structures

New Modified Deoxythymine with Dibranched Tetraethylene Glycol Stabilizes G-Quadruplex Structures

Methods for stabilizing G-quadruplex formation is a promising therapeutic approach for cancer treatment and other biomedical applications because stable G-quadruplexes efficiently inhibit biological reactions. Oligo and polyethylene glycols are promising biocompatible compounds, and we have shown th...

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Bibliographic Details
Main Authors: Hisae Tateishi-Karimata, Tatsuya Ohyama, Takahiro Muraoka, Shigenori Tanaka, Kazushi Kinbara, Naoki Sugimoto
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
branched tetraethylene glycol
g-quadruplex
stability
modified nucleic acid
ch-π interactions
Online Access:https://www.mdpi.com/1420-3049/25/3/705

Internet

https://www.mdpi.com/1420-3049/25/3/705

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