Clinical, Immunological, and Functional Characterization of Six Patients with Very High IgM Levels

Clinical, Immunological, and Functional Characterization of Six Patients with Very High IgM Levels

Very high IgM levels represent the hallmark of hyper IgM (HIGM) syndromes, a group of primary immunodeficiencies (PIDs) characterized by susceptibility to infections and malignancies. Other PIDs not fulfilling the diagnostic criteria for HIGM syndromes can also be characterized by high IgM levels an...

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Bibliographic Details
Main Authors: Vera Gallo, Emilia Cirillo, Rosaria Prencipe, Alessio Lepore, Luigi Del Vecchio, Giulia Scalia, Vincenzo Martinelli, Gigliola Di Matteo, Carol Saunders, Anne Durandy, Viviana Moschese, Antonio Leonardi, Giuliana Giardino, Claudio Pignata
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Journal of Clinical Medicine
Subjects:
hyper igm syndrome
lymphoproliferative disorders
class switch recombination
somatic hypermutation
dna repair
Online Access:https://www.mdpi.com/2077-0383/9/3/818

Internet

https://www.mdpi.com/2077-0383/9/3/818

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