HIF-1α promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19

HIF-1α promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19

Abstract Cytokine storm induced by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a major pathological feature of Coronavirus Disease 2019 (COVID-19) and a crucial determinant in COVID-19 prognosis. Understanding the mechanism underlying the SARS-CoV-2-induced cytokine storm is crit...

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Bibliographic Details
Main Authors: Mingfu Tian, Weiyong Liu, Xiang Li, Peiyi Zhao, Muhammad Adnan Shereen, Chengliang Zhu, Shanyu Huang, Siyu Liu, Xiao Yu, Miaomiao Yue, Pan Pan, Wenbiao Wang, Yongkui Li, Xulin Chen, Kailang Wu, Zhen Luo, Qiwei Zhang, Jianguo Wu
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00726-w

Internet

https://doi.org/10.1038/s41392-021-00726-w

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