Maximization of the in vitro transcorneal release and the in vivo IOP-lowering effects of Latanoprost ophthalmic gel formulations using Azone as a penetration enhancer and Carbopol-974® as a mucoadhesive.

Maximization of the in vitro transcorneal release and the in vivo IOP-lowering effects of Latanoprost ophthalmic gel formulations using Azone as a penetration enhancer and Carbopol-974® as a mucoadhesive.

The objective of this study was to maximize the in vitro transcorneal release, the intraocular pressure (IOP) lowering effect and the duration of action, of the Latanoprost acid (LAT) ophthalmic gels. The in vitro transcorneal release of LAT from a first set of gel formulations containing different...

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Bibliographic Details
Main Authors: Mohsen I. Afouna, Hatem R. Roshdy, Hany M. Ibrahim, Ashraf B. Naim, Adnan El-Marzoqi
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council
Series:Journal of Excipients and Food Chemicals
Online Access:http://jefc.scholasticahq.com/article/916-maximization-of-the-in-vitro-transcorneal-release-and-the-in-vivo-iop-lowering-effects-of-latanoprost-ophthalmic-gel-formulations-using-azone-as-a-penetration-enhancer-and-carbopol-974-as-a-mucoadhesive.pdf

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http://jefc.scholasticahq.com/article/916-maximization-of-the-in-vitro-transcorneal-release-and-the-in-vivo-iop-lowering-effects-of-latanoprost-ophthalmic-gel-formulations-using-azone-as-a-penetration-enhancer-and-carbopol-974-as-a-mucoadhesive.pdf

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