Negative Regulation of the Creatine Transporter SLC6A8 by SPAK and OSR1

Background/Aims: Transport regulation involves several kinases including SPAK (SPS1-related proline/alanine-rich kinase) and OSR1 (oxidative stress-responsive kinase 1), which are under control of WNK (with-no-K[Lys]) kinases. The present study explored whether SPAK and/or OSR1 participate in the re...

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Bibliographic Details
Main Authors: Myriam Fezai, Bernat Elvira, Jose Borras, Mossadok Ben-Attia, Zohreh Hoseinzadeh, Florian Lang
Format: Article
Language:English
Published: Karger Publishers 2014-12-01
Series:Kidney & Blood Pressure Research
Subjects:
WNK
Online Access:http://www.karger.com/Article/FullText/368465