Free and esterified oxysterol: formation during copper-oxidation of low density lipoprotein and uptake by macrophages

We have defined the lipid composition of copper-oxidized LDL (Cu-oxLDL) and a macrophage-foam cell model generated by the uptake of this modified lipoprotein. An HPLC method previously developed by our group for the measurement of lipid oxidation products of LDL was extended to permit the analysis o...

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Bibliographic Details
Main Authors: A J Brown, R T Dean, W Jessup
Format: Article
Language:English
Published: Elsevier 1996-02-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520376197