Identifying Metabolic Perturbations and Toxic Effects of <i>Rac</i>-Metalaxyl and Metalaxyl-M in Mice Using Integrative NMR and UPLC-MS/MS Based Metabolomics

Identifying Metabolic Perturbations and Toxic Effects of <i>Rac</i>-Metalaxyl and Metalaxyl-M in Mice Using Integrative NMR and UPLC-MS/MS Based Metabolomics

Although metabolic perturbations are sensitive indicators for low-dose toxic effects, the metabolic mechanisms affected by <i>rac</i>-metalaxyl and metalaxyl-M in mammals from a metabolic profiling perspective remain unclear. In this study, the metabolic perturbations and toxic effects o...

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Bibliographic Details
Main Authors: Ping Zhang, Sheng Wang, Yuhan He, Yangyang Xu, Dongmei Shi, Furong Yang, Weizhong Yu, Wentao Zhu, Lin He
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
metalaxyl
metabolomics
metabolic perturbation
amino acids
tryptophan metabolism
nmr
uplc-ms/ms
Online Access:https://www.mdpi.com/1422-0067/20/21/5457

Internet

https://www.mdpi.com/1422-0067/20/21/5457

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