Protective effect of luteolin on streptozotocin-induced diabetic renal damage in mice via the regulation of RIP140/NF-кB pathway and insulin signalling pathway

Protective effect of luteolin on streptozotocin-induced diabetic renal damage in mice via the regulation of RIP140/NF-кB pathway and insulin signalling pathway

Luteolin (LUT) is one of the most common flavonoids present in various fruits and vegetables. The effects of luteolin (LUT) on streptozotocin (STZ)-induced diabetic renal damage were investigated. LUT was orally administered at 10, 20 mg/kg/day for 4 weeks to streptozotocin-induced diabetic mice. Se...

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Bibliographic Details
Main Authors: Lvyi Chen, Guowen Tian, Weidong Tang, Wei Luo, Peng Liu, Zhanqiang Ma
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Journal of Functional Foods
Subjects:
Luteolin
Renal damage
Inflammation
RIP140
NF-кB pathway
Insulin signalling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616000268

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http://www.sciencedirect.com/science/article/pii/S1756464616000268

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