A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers.

A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers.

HIV-infected individuals maintaining undetectable viremia in the absence of therapy (HIV controllers) often maintain high HIV-specific T cell responses, which has spurred the development of vaccines eliciting HIV-specific T cell responses. However, controllers also often have abnormally high T cell...

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Bibliographic Details
Main Authors: Peter W Hunt, Alan L Landay, Elizabeth Sinclair, Jeffrey A Martinson, Hiroyu Hatano, Brinda Emu, Philip J Norris, Michael P Busch, Jeffrey N Martin, Cicely Brooks, Joseph M McCune, Steven G Deeks
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3031543?pdf=render

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http://europepmc.org/articles/PMC3031543?pdf=render

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