Depletion of proBNP1-108 in patients with heart failure prevents cross-reactivity with natriuretic peptides.

Depletion of proBNP1-108 in patients with heart failure prevents cross-reactivity with natriuretic peptides.

BACKGROUND: After synthesis by cardiomyocytes, precursor proBNP1-108 is cleaved into NT-proBNP and BNP. Recently, cross-reactivity between these assays was discussed. The aim of this study was to characterize the cross-reactivities, through a new biochemical innovative approach consisting in the tot...

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Bibliographic Details
Main Authors: François Roubille, Delphine Delseny, Jean-Paul Cristol, Delphine Merle, Nicolas Salvetat, Catherine Larue, Jean-Marc Davy, Florence Leclercq, Jean-Luc Pasquie, Luc Guerrier, Jeannette Fareh, Anne-Marie Dupuy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3775813?pdf=render

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http://europepmc.org/articles/PMC3775813?pdf=render

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