Altered Purinergic Receptor Sensitivity in Type 2 Diabetes-Associated Endothelial Dysfunction and Up<sub>4</sub>A-Mediated Vascular Contraction
Purinergic signaling may be altered in diabetes accounting for endothelial dysfunction. Uridine adenosine tetraphosphate (Up<sub>4</sub>A), a novel dinucleotide substance, regulates vascular function via both purinergic P1 and P2 receptors (PR). Up<sub>4</sub>A enhances vascu...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-12-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/19/12/3942 |