EP300 contributes to high-altitude adaptation in Tibetans by regulating nitric oxide production

EP300 contributes to high-altitude adaptation in Tibetans by regulating nitric oxide production

The genetic adaptation of Tibetans to high altitude hypoxia likely involves a group of genes in the hypoxic pathway, as suggested by earlier studies. To test the adaptive role of the previously reported candidate gene EP300 (histone acetyltransferase p300), we conducted resequencing of a 108.9 kb ge...

Full description

Bibliographic Details
Main Authors: Wang-Shan Zheng, Yao-Xi He, Chao-Ying Cui, Ouzhuluobu, Dejiquzong, Yi Peng, Cai-Juan Bai, Duojizhuoma, Gonggalanzi, Bianba, Baimakangzhuo, Yong-Yue Pan, Qula, Kangmin, Cirenyangji, Baimayangji, Wei Guo, Yangla, Hui Zhang, Xiao-Ming Zhang, Yong-Bo Guo, Shu-Hua Xu, Hua Chen, Sheng-Guo Zhao, Yuan Cai, Shi-Ming Liu, Tian-Yi Wu, Xue-Bin Qi, Bing Su
Format: Article
Language:English
Published: Science Press, PR China 2017-05-01
Series:Zoological Research
Subjects:
Tibetans
High altitude
Hypoxia
EP300
Genetic adaptation
Nitric oxide
Online Access:http://www.zoores.ac.cn/EN/abstract/abstract3818.shtml

Internet

http://www.zoores.ac.cn/EN/abstract/abstract3818.shtml

Similar Items