AT1-receptor blockade: Protective effects of irbesartan in cardiomyocytes under hypoxic stress.

AT1-receptor blockade: Protective effects of irbesartan in cardiomyocytes under hypoxic stress.

Hypoxia induces myocardial injury through the activation of inflammatory and oxidative processes. The pivotal role of the renin angiotensin system (RAS) in the pathogenesis of cardiovascular diseases has been firmly established in clinical trials and practice; in fact many experimental and clinical...

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Bibliographic Details
Main Authors: Mariarosaria Boccellino, Marina Di Domenico, Maria Donniacuo, Giuseppe Bitti, Giulia Gritti, Pasqualina Ambrosio, Lucio Quagliuolo, Barbara Rinaldi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6200178?pdf=render

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http://europepmc.org/articles/PMC6200178?pdf=render

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