Detrimental effect of renin-angiotensin blockade on progression of chronic kidney disease at later stages: A matter of dosage adjustment?

Introduction: The renoprotective effect of renin-angiotensin (RAS) blockers (angiotensin converting enzyme inhibitors and angiotensin receptor blockers) has been questioned in patients with advanced chronic kidney disease (CKD). Moreover, combination therapy (dual RAS blockade) can further accelerat...

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Bibliographic Details
Main Authors: Fernando Caravaca-Fontán, Julián Valladares, Rosa Díaz-Campillejo, Sergio Barroso, Enrique Luna, Francisco Caravaca
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Nefrología (English Edition)
Online Access:http://www.sciencedirect.com/science/article/pii/S2013251420300092