Influence of <i>N</i>-Methylation and Conformation on Almiramide Anti-Leishmanial Activity

Influence of <i>N</i>-Methylation and Conformation on Almiramide Anti-Leishmanial Activity

The almiramide <i>N</i>-methylated lipopeptides exhibit promising activity against trypanosomatid parasites. A structure–activity relationship study has been performed to examine the influences of <i>N</i>-methylation and conformation on activity against various strains of le...

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Bibliographic Details
Main Authors: Anh Minh Thao Nguyen, Skye Brettell, Noélie Douanne, Claudia Duquette, Audrey Corbeil, Emanuella F. Fajardo, Martin Olivier, Christopher Fernandez-Prada, William D. Lubell
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
almiramide
leishmaniasis
<i>N</i>-methylated peptide
Online Access:https://www.mdpi.com/1420-3049/26/12/3606

Internet

https://www.mdpi.com/1420-3049/26/12/3606

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