POCU1b, the n-Butanol Soluble Fraction of Polygoni Cuspidati Rhizoma et Radix, Attenuates Obesity, Non-Alcoholic Fatty Liver, and Insulin Resistance via Inhibitions of Pancreatic Lipase, cAMP-Dependent PDE Activity, AMPK Activation, and SOCS-3 Suppression

POCU1b, the n-Butanol Soluble Fraction of Polygoni Cuspidati Rhizoma et Radix, Attenuates Obesity, Non-Alcoholic Fatty Liver, and Insulin Resistance via Inhibitions of Pancreatic Lipase, cAMP-Dependent PDE Activity, AMPK Activation, and SOCS-3 Suppression

This study investigated the effects of the <i>n</i>-BuOH soluble fraction of Polygoni Cuspidati 80% ethanol extract (POCU1b) on high-fat diet (HFD)-induced obesity, non-alcoholic fatty liver (NAFL), and insulin resistance (IR) to find a safe and more effective agent. HPLC profiling of PO...

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Bibliographic Details
Main Authors: Junghyun Kim, Chan-Sik Kim, Kyuhyung Jo, Ik Soo Lee, Joo-Hwan Kim, Jin Sook Kim
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Nutrients
Subjects:
obesity
non-alcoholic fatty liver
insulin resistance
<i>n</i>-BuOH soluble fraction of Polygoni Cuspidati (POCU1b)
cyclic adenosine monophosphate
phosphodiesterase
Online Access:https://www.mdpi.com/2072-6643/12/12/3612

Internet

https://www.mdpi.com/2072-6643/12/12/3612

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