Next-generation sequencing for hypothesis-free genomic detection of invasive tropical infections in poly-microbially contaminated, formalin-fixed, paraffin-embedded tissue samples – a proof-of-principle assessment
Abstract Background The potential of next-generation sequencing (NGS) for hypothesis-free pathogen diagnosis from (poly-)microbially contaminated, formalin-fixed, paraffin embedded tissue samples from patients with invasive fungal infections and amebiasis was investigated. Samples from patients with...
Main Authors: | Hagen Frickmann, Carsten Künne, Ralf Matthias Hagen, Andreas Podbielski, Jana Normann, Sven Poppert, Mario Looso, Bernd Kreikemeyer |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-04-01
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Series: | BMC Microbiology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12866-019-1448-0 |
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