MicroRNA-486-5p Suppresses Lung Cancer via Downregulating mTOR Signaling In Vitro and In Vivo

MicroRNA-486-5p Suppresses Lung Cancer via Downregulating mTOR Signaling In Vitro and In Vivo

Lung cancer is one of the central causes of tumor-related deaths globally, of which non-small cell lung cancer (NSCLC) takes up about 85%. As key regulators of various biological processes, microRNAs (miRNAs) have been verified as crucial factors in NSCLC. To elucidate the role of miR-486-5p in the...

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Bibliographic Details
Main Authors: Lei Ding, Wu Tian, Hui Zhang, Wanqiu Li, Chunyu Ji, Yuanyuan Wang, Yanli Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
NSCLC
miR-486-5p
mTOR signaling
RSK
p70S6K
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.655236/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.655236/full

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