SYM 2206 (a potent non-competitive AMPA receptor antagonist) elevates the threshold for maximal electroshock-induced seizures in mice
The aim of this study was to determine the effect of SYM 2206 (a potent non-competitive AMPA receptor antagonist) on the threshold for maximal electroshock (MEST)-induced seizures in mice. Electroconvulsions were produced in mice by means of a current (sinewave, 50 Hz, maximum 500 V, strength from 4...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2014-06-01
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Series: | Current Issues in Pharmacy and Medical Sciences |
Subjects: | |
Online Access: | https://doi.org/10.2478/cipms-2014-0018 |