SYM 2206 (a potent non-competitive AMPA receptor antagonist) elevates the threshold for maximal electroshock-induced seizures in mice

The aim of this study was to determine the effect of SYM 2206 (a potent non-competitive AMPA receptor antagonist) on the threshold for maximal electroshock (MEST)-induced seizures in mice. Electroconvulsions were produced in mice by means of a current (sinewave, 50 Hz, maximum 500 V, strength from 4...

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Bibliographic Details
Main Authors: Luszczki Jarogniew J., Leszkowicz Magdalena, Kondrat-Wrobel Maria W., Florek-Luszczki Magdalena
Format: Article
Language:English
Published: Sciendo 2014-06-01
Series:Current Issues in Pharmacy and Medical Sciences
Subjects:
Online Access:https://doi.org/10.2478/cipms-2014-0018