MeDIP-seq and nCpG analyses illuminate sexually dimorphic methylation of gonadal development genes with high historic methylation in turtle hatchlings with temperature-dependent sex determination

MeDIP-seq and nCpG analyses illuminate sexually dimorphic methylation of gonadal development genes with high historic methylation in turtle hatchlings with temperature-dependent sex determination

Abstract Background DNA methylation alters gene expression but not DNA sequence and mediates some cases of phenotypic plasticity. Temperature-dependent sex determination (TSD) epitomizes phenotypic plasticity where environmental temperature drives embryonic sexual fate, as occurs commonly in turtles...

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Bibliographic Details
Main Authors: Srihari Radhakrishnan, Robert Literman, Beatriz Mizoguchi, Nicole Valenzuela
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Epigenetics & Chromatin
Subjects:
Sex-specific thermosensitive DNA methylation
Genome-wide normalized CpG content
MeDIP sequencing
Temperature-dependent and genotypic sex determination
Turtle gonadal embryonic development
Ecological genomics
Online Access:http://link.springer.com/article/10.1186/s13072-017-0136-2

Internet

http://link.springer.com/article/10.1186/s13072-017-0136-2

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