Distinct Time Course of the Decrease in Hepatic AMP-Activated Protein Kinase and Akt Phosphorylation in Mice Fed a High Fat Diet.

Distinct Time Course of the Decrease in Hepatic AMP-Activated Protein Kinase and Akt Phosphorylation in Mice Fed a High Fat Diet.

AMP-activated protein kinase (AMPK) plays an important role in insulin resistance, which is characterized by the impairment of the insulin-Akt signaling pathway. However, the time course of the decrease in AMPK and Akt phosphorylation in the liver during the development of obesity and insulin resist...

Full description

Bibliographic Details
Main Authors: Mami Shiwa, Masayasu Yoneda, Hirofumi Okubo, Haruya Ohno, Kazuhiro Kobuke, Yuko Monzen, Rui Kishimoto, Yusuke Nakatsu, Tomoichiro Asano, Nobuoki Kohno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4534138?pdf=render

Internet

http://europepmc.org/articles/PMC4534138?pdf=render

Similar Items