Filaggrin gene defects are independent risk factors for atopic asthma in a Polish population: a study in ECAP cohort.

Filaggrin gene defects are independent risk factors for atopic asthma in a Polish population: a study in ECAP cohort.

BACKGROUND: FLG null variants of which 2282del4 and R501X are the most frequent in Caucasians are established risk factors for atopic dermatitis (AD) with an effect probably mediated through impairment of epidermal barrier. Among subjects with AD FLG defects are also consistently associated with ast...

Full description

Bibliographic Details
Main Authors: Joanna Ponińska, Bolesław Samoliński, Aneta Tomaszewska, Filip Raciborski, Piotr Samel-Kowalik, Artur Walkiewicz, Agnieszka Lipiec, Barbara Piekarska, Jarosław Komorowski, Edyta Krzych-Fałta, Andrzej Namysłowski, Jacek Borowicz, Grażyna Kostrzewa, Sławomir Majewski, Rafał Płoski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3041817?pdf=render

Internet

http://europepmc.org/articles/PMC3041817?pdf=render

Similar Items