Cancer vaccines: designing artificial synthetic long peptides to improve presentation of class I and class II T cell epitopes by dendritic cells

Cancer vaccines: designing artificial synthetic long peptides to improve presentation of class I and class II T cell epitopes by dendritic cells

There is now a consensus that efficient peptide vaccination against cancer requires that peptides should (i) be exclusively presented by professional APC and (ii) stimulate both CD4 and CD8-specific T cell responses. To this aim, in recent trials, patients were vaccinated with pools of synthetic lon...

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Bibliographic Details
Main Authors: Catherine Rabu, Laurie Rangan, Laetitia Florenceau, Agnès Fortun, Maud Charpentier, Emilie Dupré, Léa Paolini, Céline Beauvillain, Estelle Dupel, Jean-Baptiste Latouche, Olivier Adotevi, Nathalie Labarrière, François Lang
Format: Article
Language:English
Published: Taylor & Francis Group 2019-04-01
Series:OncoImmunology
Subjects:
cancer vaccines
melanoma
synthetic long peptides
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1560919

Internet

http://dx.doi.org/10.1080/2162402X.2018.1560919

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